Spotted on the web: AI algorithms, tonsil proliferation, ANK2 mutations | Spectrum

Research overview

  • Drugs that act on metabotropic glutamate receptors may attenuate the behavioral effects of MECP2 gene under- or overexpression in mice, suggesting therapeutic strategies for individuals with Rett syndrome or MECP2 duplication syndrome. Neuropharmacology
  • An artificial intelligence algorithm powered by functional magnetic resonance imaging data was able to distinguish the brains of autistic boys from those of autistic girls. Spectrum covered the study last month. JAMA
  • According to a review of studies, prenatal supplements may weaken the association between maternal exposure to environmental pollutants and having a baby with a neurodevelopmental disease. Current Environmental Health Reports
  • Suicidal thoughts and suicide attempts in people with autism are linked to feeling like a burden to others and mentally rehearsing suicide plans. (If you or someone you know is having suicidal thoughts, help is available. Here’s a global directory of resources and hotlines who you can call for assistance.) Molecular autism
  • A deep learning algorithm can automate the analysis of data acquired via two-photon calcium imaging, which reveals communication between distinct neurons in living systems. Nature Communication
  • The ANK2 gene associated with autism seems to regulate the differentiation and migration of neurons during cortical development. Communications on biochemical and biophysical research
  • Autistic people say that having friendships with other autistic people helps them feel confident and happy. Autism
  • The amygdala grows too rapidly between 6 and 24 months in some children with autism, but not in children with fragile X syndrome. The American Journal of Psychiatry
  • A research consortium proposes that the oculomotor gaze index in human faces – a battery of three eye tracking assessments in children serve as a biomarker of autism in clinical trials. Molecular autism

science and society

  • The search for a new director of the US National Institutes of Health has sparked discussions about changes to its mission. STAT
  • Many Ukrainian scientists are fleeing, fighting or taking refuge with students, and many buildings and research sites have been damaged. The scientist
  • In the United States, children often wait months for an autism diagnosis and then for therapy, a situation that has only worsened during the coronavirus pandemic. CNN

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