Slow the Roll for Mammo AI; Probiotic Boost for Immunotherapy; Downside Crowdfunding





Some researchers think it’s time to slow the roll for artificial intelligence in mammography. (JAMA Health Forum)

Karyopharm Therapeutics announced plans for a new placebo-controlled randomized trial of selinexor (Xpovio) in advanced/recurrent p53 wild-type endometrial cancer to support a supplemental new drug application.

Celyad Oncology announced that the FDA placed a clinical hold on a phase Ib trial of the company’s CAR T-cell therapy for advanced cancers because of insufficient information to assess the risk to study participants.

A mid-treatment PET scan helped identify patients with HPV-positive oropharyngeal cancer who could safely receive lower-dose radiation therapy with fewer side effects. (American Society for Radiation Oncology)

A federal judge signed off on a so-called “Texas two-step” bankruptcy plan that would allow Johnson & Johnson to avoid defending itself against almost 40,000 lawsuits related to cancers allegedly caused by use of the company’s talc-containing products. (Reuters)

An experimental probiotic product showed potential for enhancing the anticancer activity of immunotherapy in renal cell carcinoma. (NatureMedicine)

Taller adults may have an increased risk of colorectal cancer. (Johns Hopkins Medicine, Cancer Epidemiology, Biomarkers & Prevention)

People who averaged 30 to 60 minutes of muscle-strengthening activity a week had as much as a 20% lower risk of premature death, including cancer death. (British Journal of Sports Medicine)

Studies involving computer simulations suggest that use of metformin to treat cancer might be harmful for some patients. (BMC Cancer)

Crowdfunding has helped relieve many cancer patients’ financial stress but some feel guilt and shame over having to ask family, friends, and even strangers for money. (University if Michigan, Journal of Cancer Survivorship)

A first-ever genetic analysis of cerebrospinal fluid from children with brain tumors uncovered a potentially useful method to identify aggressive brain cancers. (Johns Hopkins Medicine, Acta Neuropathologica Communications)

Ancient erotic pottery figurines are being used by a cancer prevention group in Peru to educate men about prostate and testicular cancer. (Reuters)

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    Charles Bankhead is senior editor for oncology and also covers urology, dermatology, and ophthalmology. He joined MedPage Today in 2007. Follow





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